Mohammad Mahdi Karimi



Computational epigenomicsVisual analytics

The overall research objective of my bioinformatics research group at the UBC Biomedical Research Centre (BRC) and the Department of Mathematics at SFU is to develop and apply new bioinformatics methods to delineate and interrogate genetic and epigenetic regulatory networks, derived from analysis of high-throughput biological data sets from human and mouse, with a focus on the impact of these processes on human health and disease.

To achieve this goal, my bioinformatics group takes advantage of immediate access to sequencing data generated by MiSeq and NextSeq Illumina sequencers as well protein expression information from CyTOF at the BRC and aims to:

(1) develop innovative and groundbreaking bioinformatics approaches for genomic, epigenomic, and transcriptomic analyses of next-generation sequencing (NGS) data

(2) transform these methods to software applications and analysis toolboxes that assist biologists in their statistical analyses of high-throughput biological data

(3) integrate and multiplex high-throughput biological data generated by various “omics” platforms at the BRC including Illumina sequencers and the CyTOF.